SNP Shot: Genomic Insights

Acral peeling skin syndrome is a skin condition where the outermost layer of skin peels off without pain. The peeling is primarily seen on the hands and feet (hence the term "acral"), but may sometimes affect the arms and legs as well. While often present at birth, the peeling can also start during childhood or adulthood. Factors like heat, humidity, moisture, and friction can worsen the skin peeling. The skin underneath may become temporarily red and itchy, but it usually heals completely without leaving scars. Notably, acral peeling skin syndrome does not cause any other health issues.

Inheritance:

The inheritance pattern of this condition is autosomal recessive. This means that a person must inherit two copies of the mutated gene, one from each parent, to develop the syndrome. The parents, who each carry only one copy of the mutated gene, are usually asymptomatic carriers of the condition.